Necrotizing sialometaplasia ns was initially defined by abrams et al. Lobular necrosis and marked squamous metaplasia of salivary gland are consistent features. Necrotizing sialometaplasia ns is a benign, selflimiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or mucoepidermoid carcinoma, both clinically and histologically, that creates diagnostic dilemma leading to unwarranted aggressive surgery. Two cases of necrotizing sialometaplasia in the palate are reported.
Necrotizing sialometaplasia is a rare disease first described in 1973. Case report necrotizing sialometaplasia of the hard palate in. All subsequent reports of necrotizing sialometaplasia stress the. Necrotizing sialometaplasia as a cause of a nonulcerated. Necrotizing sialometaplasia necrotizing sialometaplasias.
Kim h y, woo g h et al 2010 necrotizing sialometaplasia of the parotid gland in a dog. It is thought to be caused by ischemic necrosis death of tissue due to lack of blood supply of minor salivary glands in response to trauma. Necrotizing sialometaplasia in two patients with bulimia. It appears as an aggressive looking lesion in an adult possibly resembling squamous cell carcinoma and mucoepidermoid carcinoma.
Sialometaplasia of the soft palate in a 2yearold girl cases journal. Necrotizing sialometaplasia is an uncommon inflammatory condition that affects salivary glands. Necrotizing sialometaplasia is a benign inflammatory condition of the salivary gland remnants or elements, which is usually selflimiting. Necrotizing sialometaplasia of the palate sciencedirect. Oral examination revealed a nodule consisting of two lobules on the right side that measured 2. Necrotizing sialometaplasia is a rare benign and selflimiting disease, which commonly affects the minor salivary glands. Necrotizing sialometaplasia after silastic ring vertical. We report the case of a healthy 26yearold man with a painless swelling in the hard palate near the middle raphe, asymptomatic, well limited, and raised edges. The lesion was first described by aarams et al1 in 1973 and up to now more than 190 cases have been re. An association with neoplasia, such as parotid tumors, false vocal cord squamous cell carcinoma, and maxillary sinus carcinoma, is also reported. Necrotizing sialometaplasians is a benign, self limiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or mucoepidermoid carcinoma both clinically and histologically and can lead to unnecessary surgical approach.
The lesion begins acutely with swelling and pain or numbness. Mar 29, 2018 most cases of necrotizing sialometaplasia appear to arise spontaneously, whereas others are associated with a history of trauma, vomiting, 18, 19 radiation therapy, or surgery. Mar 29, 2018 necrotizing sialometaplasia ns is a nonneoplastic inflammatory condition of the salivary glands. A punctate ulcer on the posterior lateral portion of the hard palate. It mainly involves the mucoserous glands of the hard palate, but other reported sites include nasal cavity, trachea, parotid gland, sublingual gland, submandibular gland, larynx, buccal mucosa, maxillary. A 38yearold man with bilateral ulcerative painful lesions at the junction of the hard and soft. Necrotizing sialometaplasia wikipedia republished wiki 2. Necrotizing sialometaplasia ns is a benign, ulcerative lesion, usually located towards the back of the hard palate.
Necrotizing sialometaplasia in two patients with bulimia and. Necrotizing sialometaplasia ns is a selflimiting benign condition of unknown origin that affects mainly the minor salivary glands on the hard palate. Most cases of necrotizing sialometaplasia appear to arise spontaneously, whereas others are associated with a history of trauma, vomiting, 18, 19 radiation therapy, or surgery. Necrotizing sialometaplasia radiology reference article. Case report open access necrotizing sialometaplasia as a. We report the case of a healthy 25yearold caucasian woman with a threeweek history of a painless lump on her hard palate. Necrotizing sialometaplasia ns is a benign, self limiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or mucoepidermoid carcinoma both clinically and histologically and can lead to unnecessary surgical approach. The aim is to add to the existing literature on this condition. Pdf necrotizing sialometaplasia ns is a benign, selflimiting inflammatory reaction of salivary gland tissue which may mimic squamous cell.
Necrotizing sialometaplasia is a rare inflammatory necrotizing reactive process that can involve minor and major salivary glands. The relationship of its pathogenesis to its clinical characteristics. Necrotizing sialometaplasia of the palate associated with angiocentric tcell lymphoma. Necrotizing sialometaplasia of the palate j canadian dental association 2007. Necrotizing sialometaplasia ns is a nonneoplastic inflammatory condition of the salivary glands. This report presents a patient with ns who suffered from frequent bouts of vomiting subsequent to silastic ring vertical gastroplasty which resulted in remarkably low ph of the. Though minor salivary glands are frequently involved, major salivary glands are also affected less often. Necrotizing sialometaplasia is a rare, benign inflammatory disease of the minor mucous salivary glands usually caused by glandular ischemia or trauma, that can mimic malignancy, but has a selflimiting character. Jul 11, 2016 necrotizing sialometaplasia is a rare, benign, selflimiting, necrotizing process involving the minor salivary glands, mainly the mucoserous glands of the hard palate. Necrotizing fasciitis should be considered in patients gastrostomy tubes. The significance of ns resides in its clinical and histopathological resemblance to malignancy. Two cases of necrotizing sialometaplasia in the palate. Clinically and histologically necrotizing sialometaplasia may mimic malignant lesions.
This pathological lesion was first reported in 1973 by abrams et al. Contralateral recurrence of necrotizing sialometaplasia of the hard. Franklin has a great style of presentation, and i felt it was important to show others that oral. Aug 23, 2011 necrotizing sialometaplasia is a benign, selflimiting and rare inflammatory disease which, on clinical and histological examination, mimics malignant neoplasms. We present a 32yearold, white, male with rare bilateral localization of necrotizing sialometaplasia. Typically, it involves the seromucinous glands located at palate, buccal mucosa, tongue, tonsil, nasal cavity, trachea, larynx, maxillary sinus, and retromolar trigone.
Necrotizing sialometaplasia uncommon locally destructive inflammatory condition of the salivary glands. Necrotizing sialometaplasia ns is an uncommon benign reactive necrotizing inflammatory process involving minor salivary. Subacute necrotizing sialadenitis sans is a selflimiting inflammatory lesion of the minor salivary glands of unknown cause. It is thought to be the result of an ischemic event of the vasculature supplying the salivary gland lobules. Necrotizing sialometaplasia ns is a benign disease showing inflammatory response which occurs in minor salivary glands mimicking a malignant lesion both clinically as well as histopathologically. Necrotizing sialometaplasia an important diagnosis. Necrotizing sialometaplasia ns is a benign, selflimiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or. Accepted for publication 15 june 1998 necrotizing sialometaplasia ns is a benign, selflimiting, necrotizing pro cess involving mucussecreting glands, primarily the minor salivary glands. The clinical and histopathologic features of necrotizing sialometaplasia often simulate those of malignancies such as squamous cell carcinoma or salivary gland malignancy. The lesion was first described by aarams et al1 in 1973 and up to now more than 190 cases have been re ported in the literature.
A case of necrotizing sialometaplasia ns is presented in a female patient, who initially presented as a suspected head and neck malignancy. Necrotizing sialometaplasia is a benign inflammatory process that involves the minor salivary glands, primarily those of the hard palate. Experimental study of necrotizing sialometaplasia of the palate in rats. Necrotizing sialometaplasia necrotizing sialometaplasia is. Microscopically, necrotizing sialometaplasia shows marked similarity. Surgical management of necrotizing sialometaplasia of. Case report necrotizing sialometaplasia of the hard palate.
The vast majority of cases occur on the posterior lateral hard palate. In the above presented case, the patients history was suggestive of a malignant process. Mar 26, 2011 necrotizing sialometaplasia ns is a benign, self limiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or mucoepidermoid carcinoma both clinically and histologically and can lead to unnecessary surgical approach. Necrotizing sialometaplasia is a rare, benign, selflimiting, necrotizing process involving the minor salivary glands, mainly the mucoserous glands of the hard palate. Epidemiology most patients are more than 40 years of age, with. Recent references from pubmed and vetmedresource kim h y, woo g h et al 2010 necrotizing sialometaplasia of the parotid gland in a dog. Necrotizing sialometaplasia nsm is a rare benign, inflammatory disease of both major and minor salivary glands, although more commonly reported in the minor glands of the palate. Although entirely benign and requiring no treatment, due. Necrotizing sialometaplasia definition of necrotizing. Sialometaplasia definition of sialometaplasia by medical. Necrotizing sialometaplasia of the hard palate in a patient. It can be found at any site that contains salivary gland tissue, from the paranasal sinuses to the lung, but most of the cases have been re.
In 1973, abrams et al first reported this condition. Necrotizing sialometaplasia is a rare inflammatory necrotizing reactive process that can involve minor and major salivary glands find. A 38yearold man with bilateral ulcerative painful lesions at the junction of the hard and soft palate was presented. Necrotizing sialometaplasia a diagnostic conundrum. Necrotizing sialometaplasia of the hard palate in a. Necrotizing sialometaplasia was first described in 1973 by abrams, melrose and howell1.
Necrotizing sialometaplasia nsm is an uncommon inflammatory condition that affects salivary glands. Necrotizing sialometaplasia of hard palate a case report. Sialometaplasia definition at, a free online dictionary with pronunciation, synonyms and translation. Often painless, the condition is selflimiting and should heal in 610 weeks. The ensuing inflammation causes squamous metaplasia of ducts and hyperplasia of the surface stratified squamous epithelium.
It predominantly affects salivary tissue and usually involves the palate, although it has. Necrotizing sialometaplasia ns is an uncommon benign reactive necrotizing inflammatory process involving minor salivary gland that often mimics malignancy both clinically and histopathologically. We conducted an incisional biopsy and obtained a final pathological diagnosis for the palatal mass of necrotizing sialometaplasia. Subacute necrotizing sialadenitis sans is a nonspecific inflammatory. Necrotizing sialometaplasia ns is a benign, selflimiting inflammatory disease of the mucussecreting glands, and this illness mainly involves the minor salivary glands. Necrotizing sialometaplasia necrotizing sialometaplasia. We report the case of a healthy 25yearold caucasian woman with a threeweek history of a painless. Case report ct findings of necrotizing sialometaplasia. Case report necrotizing sialometaplasia accompanied by. Necrotizing sialometaplasia in the setting of acute and chronic sinusitis. The characteristic clinical presentation can perplex the clinician and may be mistaken for a malignant neoplasm, such as mucoepidermoid carcinoma, as well as. Physicians should be aware of its clinical and histological traits in order to avoid unnecessary disfiguring surgery.
Jun 23, 2014 necrotizing sialometaplasia ns is a benign, selflimiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or mucoepidermoid carcinoma, both clinically and histologically, that creates diagnostic dilemma leading to unwarranted aggressive surgery. Necrotizing sialometaplasia is a benign selflimiting process that does not require specific treatment. It is considered by some authors to be a distinct entity 1,2 and by others to be part of the spectrum of necrotizing sialometaplasia ns. Subacute necrotizing sialadenitis oral surgery, oral medicine, oral. This relatively rare condition holds diagnostic importance because of its ambiguous clinical and histopathological presentation that can be misdiagnosed clinically as neoplasia. Necrotizing sialometaplasia nsm is defined as a reactive necrotizing inflammatory process involving the minor salivary glands. We present here a case of necrotizing sialometaplasia on the soft palate, and.
Gland tissue ischaemia has been proposed as the aetiology. The cause is local ischemia producing infarction of salivary acini. Necrotizing sialometaplasia is a benign, selflimiting and rare inflammatory disease which, on clinical and histological examination, mimics malignant neoplasms. Lisa franklin is an oral pathologist who presented a forensics lecture to the residency. The lesion begins acutely with swelling and pain or.
Ct findings of necrotizing sialometaplasia a suomalainen et al 531 dentomaxillofacial radiology. Necrotizing fasciitis is a rare, but potentially devastating, sequela of vulvar skin and soft tissue infection. The lesion occurs due to vascular ischemia caused by trauma. To the best of our knowledge, only 22 cases of sans have been reported, mostly on salivary palatal glands. Necrotizing sialometaplasia, oral ulcers, minor salivary. The first patient was 29yearold female with a chief complaint of ulcer formation in the right palate. The major importance of this condition is the danger of misdiagnosis, because it may clinically and histologically mimic a malignancy. In its clinical and histological appearance, it mimics malignancy. Necrotizing sialometaplasia a diagnostic conundrum dental. Second patient was 26yearold female with a chief complaint of spontaneous pain from left palate to buccal region. Necrotizing sialometaplasia nsm is a benign, self healing lesion of salivary glands which can arise in any area containing salivary glands.
Some predisposing factors such as smoking, use of alcohol, denture wearing, recent surgery, traumatic injuries. In this report, we describe the clinical, microscopic, and ultrastructural features of 7 new cases of sans and combine them with those. Here we report a case of necrotizing sialometaplasia in a female on left side of hard palate mimicking carcinoma. A further five cases were reported the following year by dunlap and barker. Dominguezmalagon h, mosquedataylor a, canovaldez am. Case report of necrotizing sialometaplasia med oral patol oral cir. Pdf case report of necrotizing sialometaplasia researchgate. Necrotizing sialometaplasia is a reactive lesion of salivary gland origin. Apr 16, 2017 these oral pathology videos are mostly recorded in urdu, which was especially recorded to help me out in my second year so i didnt have to go through the book again and again.
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